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Deconvoluting ACS1 retrograde signaling networks that regulate leaf development

ABSTRACT: Signals originating within plastids modulate organelle differentiation by transcriptionally regulating nuclear-encoded genes. These retrograde signals are also integral regulators of plant development, including leaf morphology. The clb5 mutant displays severe leaf morphology defects due to Apocarotenoid Signal 1 (ACS1) accumulation in the developmentally arrested plastid. Transcriptomic analysis of clb5 validates ACS1 as a true retrograde signal impacting expression of hundreds of nuclear genes, including suppression of most genes encoding plastid ribosomal proteins.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE152252 | GEO | 2021/06/02

REPOSITORIES: GEO

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