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Mis-regulation of Nucleoporins 98 and 96 leads to translational stress that promotes hallmarks of tumorigenesis.

ABSTRACT: Compromising Nups 98 and 96 triggers cell death and compensatory proliferation via JNK and TNF signaling that becomes tumorigenic when apoptosis is blocked.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE152679 | GEO | 2020/09/01

REPOSITORIES: GEO

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Mis-regulation of Nucleoporins 98 and 96 leads to translational stress that promotes hallmarks of tumorigenesis.

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