Transcriptomics

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Hepatic transcriptomic alterations for decabromodiphenylethane (DBDPE) after 5-day exposure in rats


ABSTRACT: To identify liver transcripts differentially expressed due to treatment with decabromodiphenylethane (DBDPE), we collected RNA from male Harlan Sprague Dawley rats exposed to 0, 0.1, 0.97, 9.71, 97.1 or 970 mg/kg DBDPE, 5 days after exposure for animals 7 weeks of age. These samples were interrogated with the Affymetrix Rat Genome 230 2.0 GeneChip array. A total of 0,0,0,2, and 3 gene transcripts were differentially expressed due to DBDPE treatment after exposure to 0.1, 0.97, 9.71, 97.1 or 970 mg/kg DBDPE (false discovery rate (FDR) < 0.05).

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE153353 | GEO | 2020/07/15

REPOSITORIES: GEO

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