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Characterization of lung tissue-resident helper T cells

ABSTRACT: To identify the characters of tissue resident CD4 T cells following influenza virus infection, we sorted lung CD45iv-CD4+CD44hi T cells from influenza PR8 infected mice (28 d.p.i.). Then the cells were performed single cell RNA sequencing. At the result, we found clera 5 differnt clusters and each cluster represent different helper T cell types including TH1, TH17 and Treg. One cluster exhibited both tissue residency and TFH cell features. So, we identify the characters of this hybrid lung CD4 T cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE153422 | GEO | 2020/11/27

REPOSITORIES: GEO

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