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Gene Expression Profiling of Cellular Dose-Response to Hypochlorous Acid (HOCl)

ABSTRACT: Hypochlorous acid (HOCl) is a potent oxidant that is produced endogenously in mammalian tissue by phagocytes. Exogenous exposure to HOCl also can occur following inhalation of chlorine gas. HOCl has been implicated as a source of oxidative stress associated atherosclerosis and other diseases. The purpose of this study was to identify dose-dependent transitions in cellular response to hypochlorous acid (HOCl), with a focus on understanding how various cellular defense and stress dose-responses overlap.

ORGANISM(S): Mus musculus

PROVIDER: GSE15457 | GEO | 2009/04/01

SECONDARY ACCESSION(S): PRJNA115955

REPOSITORIES: GEO

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