Transcriptomics

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Next generation sequencing to reveal the transcriptome of a DUX4 inducible FSHD model


ABSTRACT: Bulk RNA sequencing was performed on a CML derived cell line, which contains an TET-ON inducible system for DUX4 inducible expression (DIE). Due to the unconventional cellular background used for the generation of an inducible FSHD cell line, bulk RNA seq was performed to determine if, and otherwise to what extend, this cellular background inteferes with the transcriptional program DUX4 is known to activate in muscle cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE154649 | GEO | 2020/07/29

REPOSITORIES: GEO

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