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CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling

ABSTRACT: CD109 is a glycosylphosphatidylinositol-anchored glycoprotein highly expressed in several types of human malignant tumors including lung cancers. We investigated the in vivo functions of CD109 protein in malignant lung tumors. CD109+/+ and CD109-/- K-ras[LSL-G12D/+];p53[fl/fl] (KP) mice were sacrificed at 20 to 23 weeks of age and total RNA was extracted from the lung tumors. SurePrint G3 Mouse GE Microarray 8×60K Ver.2.0 were performed.

ORGANISM(S): Mus musculus

PROVIDER: GSE155453 | GEO | 2020/10/01

REPOSITORIES: GEO

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