Transcriptomics

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Transcriptome analysis after BACE2 silencing in ocular melanoma cella


ABSTRACT: In order to study the mechanism of BACE2 and the development of melanoma, we established a model of low expression of BACE2 in melanoma. The results showed that the expression of tmem38b was decreased after BACE2 knockdown, and the intracellular calcium concentration was decreased. In order to reveal the interaction between BACE2 and tmem38b and the effect of intracellular Ca2 + concentration on the formation and development of melanoma, and to further explore BACE2 The relationship between the expression level and the survival time of OM patients provides new ideas for the treatment of malignant tumors

ORGANISM(S): Homo sapiens

PROVIDER: GSE155530 | GEO | 2020/12/31

REPOSITORIES: GEO

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