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Effects of PSF inhibitors on histone acetylation in prostate cancer cells [ChIP-seq]

ABSTRACT: Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. Although initially hormone-deprovation therapy is effective to inhibit cancer progression, most of cancers relapse as castration-resistant prostate cancer (CRPC). PSF is one of RNA binding proteins associated with prostate cancer progression. In this study, we examined the effect of small molecule treatment interacting with PSF on the histone acetylation status in CRPC cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE155803 | GEO | 2021/05/01

REPOSITORIES: GEO

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