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Expression data from Drosophila Kc167 cell line

ABSTRACT: The consitutive activation of the JAK/STAT signalling cascade is reponsible for the majority of meyoproliferative disorders in humans, a disease that is also conserved in Drosophila. A gain-of-function mutation in the Drosophila JAK kinase leads to blood cell (haemocyte) overproliferation which eventually is manifested as black melanotic tumors. Haemocyte-like Drosophila Kc167 cells were used to identify downstream target genes of the JAK/STAT pathway which may be responsible for tumour generation and progression.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE15584 | GEO | 2009/08/31

SECONDARY ACCESSION(S): PRJNA115591

REPOSITORIES: GEO

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