Transcriptomics

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Gene expression changes and DNA damage after ex vivo exposure of peripheral blood cells to variable CT photon spectra


ABSTRACT: In this study, we display traceable impact of energetically-varying CT irradiation on gene regulation with common upregulation of five radiation-responsive genes after single-energy (80 kV or 150kV) and dual-energy CT (80kV + 150kV) exposure. Furthermore, no evdidence for an elevated radiobiological effectiveness in respect to transcriptional impact of low energy photons emitted during dual-energy CT was found.

ORGANISM(S): Homo sapiens

PROVIDER: GSE156187 | GEO | 2021/06/01

REPOSITORIES: GEO

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