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ScRNAseq of TAZ-CAMTA1 expressing endothelial cells in vivo

ABSTRACT: TAZ-CAMTA1 is a defining genetic aberration in the vascular cancer epithelioid hemangioendothelioma. We generated a novel transgenic mouse that expresses TAZ-CAMTA1 in endothelial cells. These mice develop vascular tumors in the lung and die by average on day 40. We isolated GFP + endothelial cells from three five-week old TRE-TAZ-CAMTA1;Cdh5-tTA;TRE-GFP mice and subjected these endothelial cells to scRNA-seq via the 10X genomics platform

ORGANISM(S): Mus musculus

PROVIDER: GSE156803 | GEO | 2021/05/23

REPOSITORIES: GEO

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