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Characterisation of epithelial and mesenchymal cells in murine pancreatic tumours

ABSTRACT: We performed RNA-seq analysis on YFP+EpCAM+ and YFP+EpCAM- cell populations freshly isolated from three Pdx1-Cre;KrasLSL-G12D;Trp53fl/fl;Rosa26LSL-YFP (KPCY) murine pancreatic tumours. We compared the transcriptome between these two populations with the aim to understand their molecular interactions that could underlie epithelial-mesenchymal plasticity and tumour heterogeneity.

ORGANISM(S): Mus musculus

PROVIDER: GSE157134 | GEO | 2022/04/08

REPOSITORIES: GEO

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Mus musculus

Project description:Gene expression differences between the pancreatic tissues of Pdx1-Cre KrasLSL-G12D and Pdx1-Cre KrasLSL-G12D IKK2/betaF/F mice

| PRJNA155479 | ENA

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