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Expression of the olfactory receptors OR6X1 and OR4E2 decreases in hypothyroidism and is reversible with levothyroxine treatment in pregnancy

ABSTRACT: These libraries reflect a part of a large study. We construct transcriptome libraries, using whole blood circulating RNAs, of four healthy pregnancy (CTL) and preeclamptic women (PEC). In the manuscript, we perform an edgeR three-group analysis comparing the libraries of healthy thyroid pregnancy (HTP), gestational hypothyroidism (GHT) and preeclampsia (PEC). The HTP and GHT libraries are available in GSE147527. As a result, we obtained 1276 DEG in GHT and 1185 DEG in PEC. We also found 195 olfactory receptors common between only in GHT and PEC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE157148 | GEO | 2020/08/31

REPOSITORIES: GEO

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