ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [ATAC]
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ABSTRACT: We report the effects of ERG on prostate tumorigenesis, ERG-mediated oncogene addiction, and downstream AR signaling pathways. We determined that ERG facilitates AR-signaling and mediates transformation of prostate cells by maintaining coregulator complex formation at AR-bound sites across the genome.
ORGANISM(S): Mus musculus
PROVIDER: GSE157408 | GEO | 2020/09/04
REPOSITORIES: GEO
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