Transcriptomics

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The role of DOT1L in ovarian cancer growth and progression


ABSTRACT: Disruptor of telomeric silencing 1-like (DOT1L) expression is elevated in many cancer types including ovarian cancer. Therefore, we analyzed the role of DOT1L in ovarian cancer. Pharmacological inhibition of DOT1L expression in ovarian cancer cell lines resulted in decreased proliferation, and increased cell death.

ORGANISM(S): Homo sapiens

PROVIDER: GSE158019 | GEO | 2023/09/15

REPOSITORIES: GEO

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