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Transcriptional responses in SIX2 nephron progenitor cells following mitochondrial complex III subunit 7 (Qpc) inactivation

ABSTRACT: To identify novel transcriptional targets following Qpc inactivation. We deleteted Qpc in SIX2 nephron progenitor cells using a Six2-eGFP/cre BAC transgene. We compared SIX2-expressing progenitors from Six2-Qpc-/- kidneys with control (Six2-Qpc+/-) embryonic kidneys at E18.5.

ORGANISM(S): Mus musculus

PROVIDER: GSE158299 | GEO | 2022/06/29

REPOSITORIES: GEO

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Genome-wide maps of Six2 and b-catenin in mesenchymal nephron progenitors

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