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The effects of beta-3 adrenergic innervation on bone marrow cells

ABSTRACT: The activity of bone marrow hematopoeitic cells is tightly controlled by neurogenic innervations. As bone marrow cells mainly receive innervation from beta-3 adrenergic receptor, here we investigated the impact of beta3-adrenergic innervation on bone marrow cell transcriptome alterations. We sorted hematopoetic stem cells (HSCs) from wild type mice (control group) or Adrb3-/- mice (devoid of beta3-adrenergic receptor). Thereafter, Nanostring assessment was performed to compare the transcriptome alterations.

ORGANISM(S): Mus musculus

PROVIDER: GSE158332 | GEO | 2020/09/23

REPOSITORIES: GEO

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