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Integrative genomic strategies applied to a lymphoblast cell line model reveal specific transcriptomic signatures associated with clozapine response [methylation]

ABSTRACT: in vitro genomic analyses of clozapine response. Genome wide DNA methylation profiling was performed across several experimental conditions of clozapine exposure. LCLs were exposed to different concentrations of clozapine (vehicle (DMSO), 1x, 20x, 40x and 60 times clinical concentration) and exposure times were 24h and 96h.

ORGANISM(S): Homo sapiens

PROVIDER: GSE158716 | GEO | 2020/09/30

REPOSITORIES: GEO

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Integrative genomic strategies applied to a lymphoblast cell line model reveal specific transcriptomic signatures associated with clozapine response [expression]

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