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Adoptive transfer of type 2 diabetes by hematopoietic stem cells reprogrammed in utero by vitamin D deficiency

ABSTRACT: This study demonstrates that transplantation of fetal liver hematopoietic stem cells (FL-HSCs) from fetuses subjected to vitamin D (VD) deficiency in utero induced persistent insulin resistance to VD sufficient recipient mice. Transcriptional changes associated with intrauterine vitamin D deficiency where identified through microarray analysis of mouse BMMs from vitamin D deficient and sufficient conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE158763 | GEO | 2023/05/18

REPOSITORIES: GEO

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Transcriptomic effects of early life and peripubertal dietary vitamin D deficiency on mouse pituitary gland

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