Transcriptomics

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Multimodal profiling of 500,000 memory T cells from a tuberculosis cohort


ABSTRACT: We profiled peripheral memory T cells from donors with prior TB disease or latent infection to identify cell states associated with disease or other demographic and environmental variables. For higher-resolution definition of T cell states, we performed CITE-seq to measure single-cell mRNA and surface expression of 31 key memory T cell proteins, integrated these modalities, and quantified asssociations with variables of interest.

ORGANISM(S): Homo sapiens

PROVIDER: GSE158769 | GEO | 2021/05/24

REPOSITORIES: GEO

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