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Gene expression profile of chemically induced expandable cardiovascular progenitor cells derived from mouse fibroblasts

ABSTRACT: Cardiovascular progenitor cells (CPCs) can be reprogrammed from somatic fibroblasts by combinations of genes, providing a new avenue for cardiac regenerative therapy. Here we developed a strategy to capture chemically induced CPCs (ciCPCs) during the small molecule-induced cardiac reprogramming of mouse fibroblasts and expand these ciCPCs for a long-term in a chemically defined condition. RNA-seq analysis has been used to compare the expression profile of ciCPCs at early and late passages.

ORGANISM(S): Mus musculus

PROVIDER: GSE159081 | GEO | 2021/07/01

REPOSITORIES: GEO

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