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Rna-seq profiling of epigenetic regulator Phf2 in neural stem cells

ABSTRACT: Important hallmark of neurogenesis is activation of quiescent neural stem cells (NSC) in dentate gyrus. Precise mechanisms of NSC activation are not fully clear. In the current study we interrogate the role of homeodomain finger protein 2 (Phf2) in this process. Here we performed mouse transcriptome RNA-seq profiling of epigenetic regulator Phf2 in neural stem cells without and with knock-down in order to uncover mechanistic components/pathways affecting protein translational capacity in activated NSC.

ORGANISM(S): Mus musculus

PROVIDER: GSE159311 | GEO | 2023/05/30

REPOSITORIES: GEO

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A lysine demethylase-independent function of Phf2 regulates cohesin-mediated DNA replication for neural stem cell activation

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