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Expression profiles of tRNA-derived small RNAs and their potential roles in primary nasopharyngeal carcinoma

ABSTRACT: Transfer-RNA-Derived Small RNA (tsRNA) is a novel class of short non-coding RNA including stress-induced tRNA fragments (tiRNA) and tRNA-derived fragments (tRF). Using RNA sequencing, we evaluated the tsRNA expression profiles in the fresh nasopharyngeal carcinoma tissue specimens (n = 4) and mucosal tissue specimens (n = 4) in patients’ primary nasopharyngeal carcinoma (P-NPC) and nasopharyngitis. Bioinformatics analyses indicated that tsRNAs were the important regulators and potential new biomarkers of P-NPC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE159746 | GEO | 2022/01/11

REPOSITORIES: GEO

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