Transcriptomics

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Expression data from FITC challenged skin of CLEC4C-DTR mice vs. littermate controls treated with diptheria toxin


ABSTRACT: CLEC4C-DTR exhibit exacerbated contact hypersensitivty to the FITC hapten. Here we assess the transcriptional differences in whole skin of FITC challenged CLEC4C-DTR+ mice and DTR- mice treated with diptheria toxin. Overall, CLEC4C-DTR upregualated 439 genes and downregulated 152 genes compared to transgene negative controls, filtering output on 2 fold expression level difference and FDR<0.05.

ORGANISM(S): Mus musculus

PROVIDER: GSE160261 | GEO | 2020/10/28

REPOSITORIES: GEO

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