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Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer

ABSTRACT: Epigenetic analysis on mouse gastric organoids overexpressing either CDX2, HNF4A or control GFP. Epigenetic analyses include ATAC-seq, Cut&Run. Mouse gastric and intestinal stem cell ATAC-seq and mouse gastric antrum and intestinal villus ChIP-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE160264 | GEO | 2022/02/21

REPOSITORIES: GEO

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Distinct processes and transcriptional targets underlie CDX2 requirements in intestinal stem cells and differentiated villus cells

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