Transcriptomics

Dataset Information

0

Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [RNA-Seq]

ABSTRACT: In this project, we use a simple digestion-ligation-only Hi-C (DLO Hi-C) technology, for whole-genome chromosome conformation capture, analysis of genes expression changes and transcriptional regulatory elements involved in BMMSC differentiation. Rely on GWAS data and eQTL analysis, our findings confirmed some previously reported genes that have an effect on OP, such as TIMP-2, MMP-2 and DAAM2, TMEM241 was less reported. Furthermore, our work provide a theoretical basis for the development of OP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE160389 | GEO | 2023/02/08

REPOSITORIES: GEO

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

Other Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [Hi-C]
2023-02-08 | GSE160394 | GEO
Genomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [ATAC-Seq]
2023-02-08 | GSE160392 | GEO
Genomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C
| PRJNA673139 | ENA
Genomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [Hi-C]
| PRJNA673170 | ENA
Genomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [ATAC-Seq]
| PRJNA673171 | ENA
Genomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C [RNA-Seq]
| PRJNA673169 | ENA
Other Dynamic 3D Genome and Epigenetic Landscapes of Macrophage Cells Reprogramming Gene Expression during Differentiation and Infection (DLO Hi-C)
2023-01-18 | GSE143980 | GEO
Transcriptomics Identification of causal genes about osteoporosis associated with risk loci using DLO Hi-C
2023-02-08 | GSE160396 | GEO
Other Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture
2018-02-27 | GSE89663 | GEO
Other Dynamic 3D Genome and Epigenetic Landscapes of Macrophage Cells Reprogramming Gene Expression during Differentiation and Infection [sciDLO Hi-C]
2022-10-01 | GSE159501 | GEO