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Controlled hydroxylations of diterpenoids allow for plant chemical defense without autotoxicity

ABSTRACT: Disturbing the biosynthetic pathway of 17-hydroxylgeranyllinalool diterpene glycosides (HGL-DTGs), including silencing NaCYP736A, caused severe plant autotoxicity. This autotoxicity can be restored by co-silencing the upstream biosynthetic genes, like geranyllinalool synthase (GLS). Through comparing the transcriptome data of EV, VIGS-GLS, VIGS-CYP736A and VIGS-GLS&CYP736A, we tried to figure out the potential mechanism of this autotoxicity.

ORGANISM(S): Nicotiana attenuata

PROVIDER: GSE160453 | GEO | 2020/11/17

REPOSITORIES: GEO

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