BMP4 effect on gene expression program in human primary epidermal keratinocytes and dermal fibroblasts

ABSTRACT: BMP signalling is a potent regulator of skin morphogenesis, homeostasis and remodelling. However, molecular mechanisms underlying its involvement in regulating gene expression programs in keratinocytes and fibroblasts remain largely unknown. We analyzed the effect of BMP4 tratment on gene expression programs in human primary epidermal keratinocyte and dermal fibroblasts cultures. We identified specific changes in gene expression programs for each cell type.

ORGANISM(S): Homo sapiens

PROVIDER: GSE16111 | GEO | 2009/06/15

SECONDARY ACCESSION(S): PRJNA117225

REPOSITORIES: GEO