Transcriptomics

Dataset Information

0

Identification of differentially expressed lncRNAs and coding mRNAs in SNAI1/2 overexpression cell line


ABSTRACT: The oncogene SNAI2 is known to be a master transcription factor that regulates a broad range of cellular processes, including epithelial-mesenchymal transition (EMT). As a transcription factor, there is no doubt that SNAI1/2 could directly regulate the expression of thousands of genes, including lncRNAs. In this study, we took SNAI1/2 as a breakthrough point to screen and identify lncRNAs regulated by SNAI2 in GC. Our data showed that overexpression of SNAI2 caused a 1.5-fold change in the expression of about 654 lncRNAs (|Log2FC| >0.5), and a 2-fold change in the expression of about 123 lncRNAs (|Log2FC| >1).

ORGANISM(S): Homo sapiens

PROVIDER: GSE161551 | GEO | 2021/10/01

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2013-09-30 | GSE40690 | GEO
2023-03-02 | GSE223683 | GEO
2023-03-02 | GSE223681 | GEO
2013-09-30 | E-GEOD-40690 | biostudies-arrayexpress
2023-03-02 | GSE223682 | GEO
2012-07-05 | GSE38236 | GEO
2012-07-04 | E-GEOD-38236 | biostudies-arrayexpress
2012-07-04 | E-GEOD-24904 | biostudies-arrayexpress
2012-01-13 | GSE35074 | GEO
2019-03-04 | GSE111386 | GEO