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Transcriptomic and epigenetic investigation of Zika virus (ZIKV) infection in human monocyte-derived dendritic cells and other cell types

ABSTRACT: Dendritic cells are key targets for ZIKV infection. To identify host pathways manipulated by ZIKV in dendritic cells, we developed a system that enables characterization of genome-wide transcriptional and epigenetic changes in ZIKV-infected and neighboring, uninfected primary human dendritic cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE161783 | GEO | 2022/08/18

REPOSITORIES: GEO

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Genome-wide RNA-seq and Epigenetic analysis of human monocyte derived macrophage responses to Zika virus infection

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