Transcriptomics

Dataset Information

0

The impact of influenza pulmonary infection and inflammation on vagal bronchopulmonary sensory neurons


ABSTRACT: Influenza A virus (IAV) is rapidly detected in the airways by the immune system, with resident parenchymal cells and leukocytes orchestrating viral sensing and the induction of antiviral inflammatory responses. The airways are innervated by heterogenous populations of vagal sensory neurons which also play an important role in pulmonary defense. How these neurons respond to IAV respiratory infection remains unclear. Here, we use a murine model to provide the first evidence that vagal sensory neurons undergo significant transcriptional changes following a respiratory IAV infection. RNA sequencing on vagal sensory ganglia showed that IAV infection induced the expression of many genes associated with an antiviral and pro-inflammatory response

ORGANISM(S): Mus musculus

PROVIDER: GSE161878 | GEO | 2021/06/20

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-03-06 | GSE252735 | GEO
2019-07-16 | GSE134260 | GEO
2020-04-05 | GSE145216 | GEO
2024-06-05 | GSE268741 | GEO
| PRJNA679770 | ENA
2024-05-10 | GSE267231 | GEO
2019-05-20 | GSE124312 | GEO
2022-06-16 | GSE206052 | GEO
2019-11-14 | GSE138651 | GEO
2020-03-15 | GSE141399 | GEO