Transcriptomics

Dataset Information

0

CircRNA expression profiles in peripheral blood mononuclear cells of patients with large-artery atherosclerotic stroke


ABSTRACT: Circular RNAs (circRNAs) are a recently discovered non-coding RNA isoform capable of regulating neurological disease incidence. The present study was designed to characterize the circRNA expression profiles present in large-artery atherosclerosis (LAA)-type acute ischemic stroke patients. Using a RNA-seq approach, we characterized circRNA expression profiles in 5 LAA-stroke patients and 4 controls. We identified 182 and 176 circRNAs that were up- and down-regulated, respectively, in LAA-stroke patients relative to controls. Enrichment analyses suggested these differentially expressed circRNAs to primarily be associated with chromatin modification, autophagy, platelet activation, and neural precursor cell proliferation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE161913 | GEO | 2021/12/31

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-02-02 | GSE190869 | GEO
2021-06-08 | GSE173719 | GEO
2015-01-06 | E-GEOD-63823 | biostudies-arrayexpress
2020-01-23 | GSE138849 | GEO
2021-06-24 | GSE178764 | GEO
2019-04-06 | GSE129409 | GEO
2015-04-24 | E-GEOD-65926 | biostudies-arrayexpress
2022-01-28 | GSE195442 | GEO
2020-11-13 | GSE161361 | GEO
2021-08-26 | PXD025203 | Pride