Transcriptomics

Dataset Information

0

ASPSCR1-TFE3 reprograms transcription by organizing enhancers around hexameric VCP [RNA-Seq, FUUR1_KD]


ABSTRACT: ChIPseq experiments identify that ASPSCR1-TFE3 defines active enhancers across the genome and co-distributes with VCP/p97. RNAseq after knock-down of ASPSCR1-TFE3 or VCP, inhibition of VCP, or overexpression of each in alveolar soft part sarcoma cell lines demonstrates their co-dependence. HiChIP defines chromatin conformations that surround ASPSCR1-TFE3 targets and are lost on VCP knock-down.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162488 | GEO | 2023/01/01

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-01-01 | GSE162068 | GEO
2023-01-01 | GSE162479 | GEO
2023-01-01 | GSE162483 | GEO
2023-01-01 | GSE162477 | GEO
2023-01-01 | GSE162476 | GEO
2023-01-01 | GSE162482 | GEO
2023-01-01 | GSE162481 | GEO
2023-01-01 | GSE162480 | GEO
2023-01-01 | GSE162486 | GEO
2023-01-01 | GSE162576 | GEO