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Neuronal-like differentiation of A549 cells in response to PRMT1 knockdown

ABSTRACT: Formerly we found that cancer-promoting factors, such as some typical epigenetic modification factors, are neural specific or enriched in embryonic neural cells, and play a key role in conferring the property of nerual stemness to cancer cells or in maintaining neural stemness in neural stem/progenitor cells. Our recent study demonstrated that PRMT1, a protein arginine methyltransferase, serves also to maintain neural stemness in either neural stem/progenitor cells or cancer cells. We used microarray to analyze global gene expression change in A549 cells after PRMT1 knockdown.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162840 | GEO | 2020/12/09

REPOSITORIES: GEO

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