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Interdependence between histone marks and steps in Pol II transcription

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Equus caballus Homo sapiens

PROVIDER: GSE163049 | GEO | 2020/12/12

REPOSITORIES: GEO

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Interdependence between histone marks and steps in Pol II transcription [Antczak.submission]

Project description:ChRO-seq provides quantative information about gene expression levels in liver tissue taken at necropsy from two healthy Quarter Horse mares.

2020-12-12 | GSE163048 | GEO

Interdependence between histone marks and steps in Pol II transcription [Danko.submission]

Project description:We trained sensitive machine learning models that decompose maps of primary transcription into ChIP-seq profiles representing 9 distinct histone modifications. We show that transcription measured using precision run-on and sequencing (PRO-seq) can recover the pattern of active histone modifications at nucleosome resolution and with an accuracy that rivals the correlation between independent ChIP-seq experiments in holdout cell types. To define the nature of the causal relationship between histone modifications and transcription, we perturbed transcription and examined the genomic distribution of four active and one repressive histone modification: H3K4me1, H3K4me3, H3K27ac, H3K36me3, H3K27me3.

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Interdependence between histone marks and steps in Pol II transcription

Project description:Interdependence between histone marks and steps in Pol II transcription

| PRJNA684561 | ENA

Interdependence between histone marks and steps in Pol II transcription [Antczak.submission]

Project description:Interdependence between histone marks and steps in Pol II transcription [Antczak.submission]

| PRJNA684563 | ENA

Interdependence between histone marks and steps in Pol II transcription [Danko.submission]

Project description:Interdependence between histone marks and steps in Pol II transcription [Danko.submission]

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Pol II and its associated epigenetic marks are present at pol III-transcribed non-coding RNA genes

Project description:This SuperSeries is composed of the SubSeries listed below.

2010-04-25 | GSE20072 | GEO

The RSC Complex localizes to coding sequences to regulate Pol II and histone occupancy

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-11-24 | E-GEOD-62522 | biostudies-arrayexpress

The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-06-20 | GSE185241 | GEO

Genome-wide effects of Spt6 on RNA pol II and Histone H3 occupancy in budding yeast

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-08-16 | E-GEOD-49928 | biostudies-arrayexpress

Pol II and its associated epigenetic marks are present at Pol III-transcribed noncoding RNA genes.

Project description:Epigenetic control is an important aspect of gene regulation. Despite detailed understanding of protein-coding gene expression, the transcription of noncoding RNA genes by RNA polymerase III (Pol III) is less well characterized. Here we profile the epigenetic features of Pol III target genes throughout the human genome. This reveals that the chromatin landscape of Pol III-transcribed genes resembles that of Pol II templates in many ways, although there are also clear differences. Our analysis also uncovered an entirely unexpected phenomenon: namely, that Pol II is present at the majority of genomic loci that are bound by Pol III.

| S-EPMC2917008 | biostudies-literature

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