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Role of ZBP1 in myeloma cell biology

ABSTRACT: Whole transcriptome of ZBP1-depleted myeloma cells was analysed using a high-throughput RNA-seq approach. ZBP1 was depleted by 2 different shRNAs in MM1.S and H929 cells, and total RNA was isolated on day 4 post-lentiviral transduction. Poly A-tail enriched RNA was sequenced and the analysis of commonly regulated genes by both shRNAs from 2 independent experiments revealed that ZBP1 regulates genes that are involved in cell cycle regulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE163496 | GEO | 2021/02/28

REPOSITORIES: GEO

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