Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription landscape of adipose tissue and tumor in response to adipose stromal cell depletion

ABSTRACT: Mice grafted with Myc-Cap tumor were treated (3 weeks) with a pro-apoptotic peptide D-CAN targeting adipose stromal cells or PBS (control).

ORGANISM(S): Mus musculus

PROVIDER: GSE163701 | GEO | 2020/12/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcription landscape of adipose tissue and tumor in response to adipose stromal cell depletion

Project description:Transcription landscape of adipose tissue and tumor in response to adipose stromal cell depletion

| PRJNA687226 | ENA

The small and large intestine contain transcriptionally related mesenchymal stromal cell subsets that derive from embryonic Gli1+ mesothelial cells [scRNA-Seq]

Project description:One round of grafted SI and LI presorted YFP+ mesenchymal stromal cells were subjected to scRNA-seq.

2023-03-17 | GSE181707 | GEO

Expression data from adipose stromal cells

Project description:Adipose stromal cells are adipocytes progenitors lying in the stroma vascular fraction of adipose tissue. They can also be released into the circulation upon dietary challenges. We used microarrays to compare the global programme of gene expression between adipose stromal cells originating from murine subcutaneous and perigonadal adipose depots

2019-04-04 | GSE127928 | GEO

Expression data from adipose stromal cells

Project description:Expression data from adipose stromal cells

| PRJNA525824 | ENA

Depletion of ADAM12+ MSCs normalizes the tumor stromal microenvironment

Project description:This study investigates transcriptomic changes occurring in PDPN+PDGFRa+ stromal cells from murine B16-OVA melanomas (MO5) when ADAM12+ mesenchymal stromal cells (MSCs) are depleted.

2023-10-05 | GSE206794 | GEO

Diabetic microenvironment deteriorates the regenerative capacities of adipose mesenchymal stromal cells

Project description:Human adipose mesenchymal stromal cells cutltured in culture media containing diabetic patient serum or normal indvidual serum as control for 6 days and 1 month period

2024-06-22 | PXD036116 | Pride

Study of bone marrow Nestin+ mesenchymal stromal cells in control and leukemic mice

Project description:NRAS-G12D+ mice show reduced numbers of mesenchymal stromal cells together with increased apoptotic rates as compared to healthy controls.

2022-11-14 | GSE157038 | GEO

Adipose-derived stromal/stem cells (ASC)

Project description:Adipose-derived stromal/stem cells (ASC) capable of multipotential differentiation can be isolated with high yield from human subcutaneous lipoaspirates. This study reports our recent experience isolating and immunophenotypically characterizing ASCs from >60 human subjects

2010-10-01 | GSE18391 | GEO

Graphene Oxide Substrate Promotes Neurotrophic Factor Secretion and Survival of Human Schwann-Like Adipose Mesenchymal Stromal Cells - RNAseq

Project description:Mesenchymal stromal cells from adipose tissue (AD-MSCs) exhibit favourable clinical traits for autologous transplantation and can develop a ‘Schwann-like’ phenotype (sAD-MSCs) to improve peripheral nerve regeneration, where severe injuries yield insufficient recovery. However, sAD-MSCs regress without biochemical stimulation and detach from conduits under unfavourable transplant conditions, negating their paracrine effects. Graphene-derived materials support AD-MSC attachment, regulating cell adhesion and function through physiochemistry and topography. We report graphene oxide (GO) as a suitable substrate for human sAD-MSCs incubation towards severe peripheral nerve injuries, through evaluating transcriptome changes, neurotrophic factor expression over a 7-day period, and cell viability in apoptotic conditions. Transcriptome changes from GO incubation across four patients were minor compared to biological variance.

2021-03-08 | E-MTAB-10078 | biostudies-arrayexpress

Single-cell sequencing of adipose-derived mesenchymal stromal cells and dermal fibroblasts

Project description:Single-cell sequencing of adipose-derived mesenchymal stromal cells and fibroblasts.

| EGAS00001006954 | EGA