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Age-Dependent Transcriptional Alterations in Cardiac Endothelial Cells [scRNA-seq]

ABSTRACT: Purpose: The goal of this study is to determine alterations in heart endothelial cell transcripts and cell populations associated with aging. Methods: Endothelial single cell mRNA profiles of 3 month and 24 month old wild-type mice were generated by 10X Genomics Results: Using an optimized data analysis workflow, we mapped about 50 thousand reads per cell Conclusions: Our study represents the first analysis of aged cardiac endothelial cell transcriptomes using single cell RNA-seq technology, identifiying specific transcripts and cell populations affected by age.

ORGANISM(S): Mus musculus

PROVIDER: GSE163822 | GEO | 2021/05/28

REPOSITORIES: GEO

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Age-Dependent Transcriptional Alterations in Cardiac Endothelial Cells [bulk RNA-seq]

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