Methylation profiling

Dataset Information

0

DNA methylation of fibroblasts from Cockayne syndrome and UV-sensitivity syndrome patients [EPIC]


ABSTRACT: Cockayne syndrome (CS) is a rare genetic disorder caused by mutation of the DNA repair and chromatin remodelling proteins CSA or CSB. Increasing evidences indicate that the progeroid phenotype of CS cannot be solely ascribed to impaired DNA repair, and UV-sensitivity syndrome (UVSS) patients that are also mutated for CSA or CSB do not age prematurely. Epigenetic modifications constitute a hallmark of ageing. We assessed genome-wide DNA methylation (DNAm) at single-nucleotide resolution on fibroblasts derived from CS versus UVSS patients and healthy donors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE163840 | GEO | 2023/12/24

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-12-24 | GSE163839 | GEO
2006-07-14 | GSE3407 | GEO
2007-07-03 | E-GEOD-3407 | biostudies-arrayexpress
2020-03-16 | GSE122736 | GEO
2021-10-11 | PXD023472 | Pride
2017-12-01 | GSE87562 | GEO
2017-12-01 | GSE87540 | GEO
2014-12-22 | GSE62194 | GEO
2020-12-22 | GSE144557 | GEO
2020-12-22 | GSE144556 | GEO