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Knowk-down of EWSR1-FLI1 in Ewing sarcoma cell lines (RNA-seq)

ABSTRACT: EWSR1-FLI1 is a chimeric transcription factor resulting from the pathognomonic translocation present in Ewing sarcoma cells. Here, we silenced EWSR1-FLI1 in different Ewing sarcoma cell lines. RNA from SKNMC, TC71 and MHH-ES1 cells was extracted 96h post transfection (siCT or siEWSR1-FLI1) or prior doxycycline (day 0) and 7 days after inducing silencing of EWSR1-FLI1 with doxycycline in ASP14 cells. RNA-seq was performed for all conditions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE164372 | GEO | 2022/05/09

REPOSITORIES: GEO

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