Transcriptomics

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Effect of Insulin receptor deletion in hepatocytes on liver gene expression at different time point in mice either fed ad libitum or upon day-restricted feeding


ABSTRACT: To assess the consequences of IR deletion on gene expression using microarray and its contribution of IR to the control of rythmic liver gene expression, wild-type (IRhepWT) and KO (IRhepKO) mice were either fed ad libitum or submitted to day-restricted feeding (as described by Damiola et al., 2000). Liver samples were collected around the clock (ZT0, ZT04, ZT08, ZT12, ZT16, ZT20).

ORGANISM(S): Mus musculus

PROVIDER: GSE165155 | GEO | 2023/01/01

REPOSITORIES: GEO

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