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Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

ABSTRACT: Infinium Methylation 450 K was used to profile the epigenetic differences in 24 children between two timepoints: 12 months (baseline group) and 24 months and to elucidate the methylation differences between 12 high and 12 low PCV-13 booster vaccine responders, in order to identify pathways that show significant changes over time and those that are associated with a more robust immune response.

ORGANISM(S): Homo sapiens

PROVIDER: GSE165170 | GEO | 2021/02/04

REPOSITORIES: GEO

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