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Lipid signalling enforces functional specialization of Treg cells in tumours [scRNA-seq]

ABSTRACT: Metabolic reprogramming enforces Treg cell functional specialization in tumors by coordinating fatty acid biosynthesis and inhibitory receptor signaling pathways. These findings point to new avenues to selectively targeting intratumoral Treg cells for cancer therapy.

ORGANISM(S): Mus musculus

PROVIDER: GSE165258 | GEO | 2021/02/24

REPOSITORIES: GEO

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