Effect of Lenalidomide on human macrophages.

ABSTRACT: Lenalidomide, an IMiD® immunomodulatory agent used for the treatment of multiple myeloma (MM),is believed to target the stromal support, but its precise mechanism on the phenotype or the effector functions of macrophages is still unclear. To investigate the effect of lenalidomide on macrophages, M-CSF generated macrophages were treated with Lenalidomide and analyzed by RNA-seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE165332 | GEO | 2021/01/23

REPOSITORIES: GEO