Differential gene expression analysis in eosinophilic and mixed granulomatous lung inflammation
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ABSTRACT: Alteration in the gene expression level in the lungs are thought to play a crucial role during the development of asthma and airway hyperresponsiveness. House dust mite induced allergic asthma is a Th2-lymphocyte driven inflammation characterized by airway hyperresponsiveness and eosinophilia while c-di-GMP, which is a potent mucosal adjuvant, induces a Th1-Th17 response accompanied by neutrophilia along with a low Th2 response. We aimed to identify changes in the expression of genes important in asthma pathology via targeted gene expression arrays.
ORGANISM(S): Mus musculus
PROVIDER: GSE165969 | GEO | 2021/02/03
REPOSITORIES: GEO
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