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Gene Expression data from HuR-RIP-microarray from human PDAC, Mia PaCa-2 cell line

ABSTRACT: RNA binding protein, Human Antigen R (HuR/ELAVL1), regulates mRNA stability of key species involved in pancreatic ductal adenocarcinoma (PDAC) cell survival under conditions of chemotherapeutic stress, hypoxia, low glucose environment. We used RNA immunoprecipitation-microarray or RNP-IP from cytoplasmic extracts of PDAC cell lines exposed to chemotherpaeutic stress (olaparib and gemcitabine) to evaluate whole transcriptome gene expression profile associated with HuR and find novel trargtes associated with DNA repair functions of HuR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE166951 | GEO | 2022/04/20

REPOSITORIES: GEO

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Gene Expression data from HuR-RIP-microarray from human PDAC, Mia PaCa-2 cell line

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