Transcriptomics

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RNA-seq in QGY-7703 cell line before and after PRMT7 knockdown


ABSTRACT: To explore the mechanism by which PRMT7 regulates HCC cell malignant phenotypes, we performed RNA-seq in QGY-7703 cells before and after PRMT7 knockdown to identify the affected signaling pathways. 296 differentially expressed genes were identified in PRMT7-downregulated cells (Figure 6A) and these genes were enriched in cancer-related pathways including MAPK signaling pathway, p53 signaling pathway, and FoxO signaling pathway (Figure 6B), as revealed by DAVID KEGG analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE167432 | GEO | 2021/02/25

REPOSITORIES: GEO

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