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Valine tRNA biogenesis and bioavailability regulates mitochondrial complex I levels in acute leukemia [CRISPR screen]

ABSTRACT: We report the effects of gene knockout via CRISPR/Cas9 system targeting either the whole genome or specifically genes involved in tRNA biogenesis in T cell acute lymphoblastic leukemia cell lines under normal versus valine limited media.

ORGANISM(S): Homo sapiens

PROVIDER: GSE167534 | GEO | 2021/10/27

REPOSITORIES: GEO

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