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Whole Transcriptome Sequencing Identifies Key circRNAs, lncRNAs and miRNAs Regulating Neurogenesis in Developing Mouse Retina

ABSTRACT: Retina is the fundamental unit of central nervous system, whose development is orchestrated by the intricate crosstalk of diverse RNA species. However, the molecular complexity of neural retina development remains poorly elucidated, limiting the therapy of retinal neurodegenerative diseases. Herein, we performed whole transcriptome sequencing of mouse retina in E14.5, P1, P7, P12, P17 and adult. The circRNA, lncRNA, miRNA and mRNA expression profiles of the developing retina were comprehensively characterized and the differentially expressed RNAs were screened.

ORGANISM(S): Mus musculus

PROVIDER: GSE168093 | GEO | 2021/06/18

REPOSITORIES: GEO

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